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. 2017 May 15;6(7):748–759. doi: 10.1016/j.molmet.2017.05.006

Figure 1.

Figure 1

Neonatal Ex-4 decreases adiposity in male and female mice. (A–H) Analysis of C57BL/6N male (A–D) and female (E–H) mice given daily injections of vehicle (saline) or Ex-4 (1 nmol/kg birth weight). Mean body weight of male (A) and female (E) mice at postnatal days 1, 17, and 28. n = 4–9 mice per gender and treatment group. P28 fat pad weights from male (B) and female (F) mice normalized to body weight. n = 4–9 mice per gender and treatment group. NMR analysis of 25 day old male (C) and female (G) mice. n = 6–9 mice/group. Plasma leptin measured in P28 male (D) and female (H) mice. n = 4–9 mice per gender and treatment group. All data are expressed as mean ± SEM; *, p < 0.05, relative to corresponding vehicle (Two-tailed Student's t test).