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Neonatal Ex-4 durably reduces NPY fiber density in the PVH. Histological analysis of NPY-IR in the PVH at 4, 8–10, and 42 weeks in neonatal vehicle or Ex-4 treated female mice. Images representative of n = 3–4. Mice weaned at P21 on to standard chow (4 and 8–10 weeks) or LFD (42 weeks). Scale Bar 150 μm.
