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. 2017 May 17;6(7):664–680. doi: 10.1016/j.molmet.2017.05.007

Figure 2.

Figure 2

NOD-IGF1 mice have normal insulinemia and are glucose tolerant. (A) Serum insulin levels in fed conditions in normoglycemic (NG) and hyperglycemic (HG) NOD mice and in NOD-IGF1 mice at 15 and 30 weeks of age (n = 4–8/group). (B) Glucose tolerance test performed in 15-week-old NOD NG mice (n = 5), in NOD HG mice (n = 2) and in NOD-IGF1 mice (n = 8). (C) Glucose tolerance test performed in 30-week-old NOD NG mice (n = 2) and NOD-IGF1 mice (n = 9). (D) Serum concentrations of triglycerides, free-fatty acids, and β-hydroxybutyrate in fed conditions at 15 weeks of age in all experimental groups (n = 5/group). Results are expressed as mean ± SEM. *P < 0.05 vs. NOD NG; #P < 0.05 vs. NOD HG. ND: Non-detected.