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. 2017 Apr 24;98(2):52–66. doi: 10.1111/iep.12222

Table 2.

Predicted functional partners of ADO

S. No Proteins Details of interacting proteins String score Prediction tools
1. Inline graphic CSAD Cysteine sulphinic acid decarboxylase (520 aa) 0.913 STRING
2. Inline graphic GAD1 Glutamate decarboxylase 1 (brain, 67 kDa); catalyses the production of GABA (594 aa) 0.900 STRING
3. Inline graphic GAD2 Glutamate decarboxylase 2 (pancreatic islets and brain, 65 kDa); catalyses the production of GABA (585 aa) 0.900 STRING
4. Inline graphic CDON CDON homolog (mouse); component of a cell surface receptor complex that mediates cell–cell interactions between muscle precursor cells. Promotes differentiation of myogenic cells (1264 aa) 0.785 STRING
5. Inline graphic ADK Adenosine kinase; ATP‐dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives. Serves as a potential regulator of concentrations of extracellular adenosine and intracellular adenine nucleotides (362 aa) 0.648 STRING
6. Inline graphic RPIA Ribose 5‐phosphate isomerase A (311 aa) 0.655 STRING
7. Inline graphic C3 Complement component 3; C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation, C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates (1663 aa) 0.610 STRING
8. Inline graphic TRIM33 Tripartite motif containing 33: acts as an E3 ubiquitin‐protein ligase and promotes SMAD4 ubiquitination, nuclear exclusion and degradation via the ubiquitin‐proteasome pathway. (1127 aa) 0.583 STRING
9. Inline graphic ADORA2B Adenosine A2b receptor; receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (332 aa) 0.581 STRING
10. Inline graphic ADORA1 Adenosine A1 receptor; receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase (326 aa) 0.525 STRING
11. UBC Polyubiquitin‐C; ubiquitin – I2D
12. KCNJ10 Potassium inward‐rectifying channel subfamily J member 10 – Biogrid
13. FAM67B Family with sequence similarity 76, member B – Biogrid
14. C50RF24 Chromosome 5 open reading frame 24 – Biogrid