Table 2.
Median sCD30 levels according to demographic characteristics of kidney allograft recipients at baseline.
| Patient's characteristics | n | Pretransplant sCD30 | P value | n | Posttransplant sCD30 | P value |
|---|---|---|---|---|---|---|
| Age | 21–40 (n = 23) | 54.8 (36.9–96.6)∗ | 0.151 | 21–39 (n = 17) | 21.4 (15.7–40.1) | 0.817 |
| >40 (n = 22) | 42.0 (30.8–60.2) | >39 (n = 16) | 23.3 (14.8–37.5) | |||
| Gender | Female (n = 20) | 42.1 (29.1–71.2) | 0.595 | Female (n = 17) | 26.6 (21.2–39.7) | 0.260 |
| Male (n = 25) | 51.6 (36.2–64.2) | Male (n = 16) | 18.4 (12.9–38.8) | |||
| Donor source | Living (n = 6) | 85.6 (40.9–159.9) | 0.038 | Living (n = 4) | 39.4 (30.3–45.0) | 0.133 |
| Deceased (n = 39) | 48.3 (27.3–64.2) | Deceased (n = 29) | 21.4 (13.4–37.6) | |||
| Donor age | 17–38 (n = 22) | 54.8 (36.2–70.6) | 0.960 | 17–39 (n = 17) | 21.4 (13.4–40.1) | 0.709 |
| >38 (n = 23) | 45.0 (29.7–79.5) | >39 (n = 16) | 25.1 (15.9–38.7) | |||
| Primary disease | GN (n = 37) | 51.0 (30.8–70.7) | 0.782 | GN (n = 28) | 22.2 (14.6–38.7) | 0.643 |
| non-GN (n = 8) | 45.8 (38.8–78.4) | non-GN (n = 5) | 23.5 (16.1–45.3) | |||
| Dialysis modality | HD (n = 42) | 50.2 (30.8–70.7) | 0.814 | HD (n = 30) | 21.4 (13.4–37.6) | 0.075 |
| PD (n = 3) | 40.9 (40.1–88.5) | PD (n = 3) | 44.8 (34.0–52.9) | |||
| Dialysis duration | ≤18 m (n = 22) | 50.6 (32.2–71.7) | 0.711 | <18 m (n = 16) | 30.3 (19.2–42.5) | 0.146 |
| >18 m (n = 23) | 48.3 (30.8–70.6) | ≥18 m (n = 17) | 19.9 (12.4–28.0) | |||
| Pregnancies | Yes (n = 5) | 60.2 (40.9–70.7) | 0.661 | Yes (n = 4) | 27.7 (16.5–45.4) | 0.730 |
| No (n = 40) | 48.9 (31.5–71.1) | No (n = 29) | 23.1 (15.7–39.7) | |||
| Transfusions | Yes (n = 8) | 47.5 (42.0–58.2) | 0.988 | Yes (n = 7) | 23.5 (15.7–39.7) | 0.682 |
| No (n = 37) | 51.0 (27.3–72.6) | No (n = 26) | 22.2 (13.4–40.1) | |||
| Previous transplants | Yes (n = 2) | 57.6 (51.0–64.2) | 0.618 | Yes (n = 2) | 20.6 (13.4–27.8) | 0.689 |
| No (n = 43) | 48.3 (30.8–71.7) | No (n = 31) | 23.1 (15.7–40.1) | |||
| Anti-CD25 antibodies | Yes (n = 36) | 48.9 (29.1–67.4) | 0.567 | Yes (n = 27) | 21.4 (13.4–37.4) | 0.089 |
| No (n = 9) | 51.6 (40.1–72.6) | No (n = 6) | 46.0 (23.5–50.7) |
sCD30: soluble CD30; GN: glomerulonephritis; HD: hemodialysis; PD: peritoneal dialysis; m: months; n: number of patients investigated. ∗Median (interquartile range); P values: significance of differences between subgroups of patients.