Table 5.

Summary of the main variants found in this clinical cohort

Gene	Mutation	Classification	Type
BRCA1 (NM_007294.3)	c.441+2T>A	Pathogenic	Intronic (splice donor variant)
	c.68_69delAG: p.Glu23Valfs*17	Pathogenic	Frameshift
	c.5365G>T: p.Ala1789Ser	VUS	Missense
BRCA2 (NM_000059.3)	c.4965C>: p.Y1655*	Pathogenic	Nonsense
	c.8878C>T: p.Gln2960*	Pathogenic	Nonsense
	c.9382C>T: p.Arg3128*	Pathogenic	Nonsense
	c.1813dupA: p.Ile605Asnfs*11	Pathogenic	Frameshift
	c.9004G>A: p.Glu3002Lys	Pathogenic	Missense
	c.8850G>T: p.Lys2950Asn	VUS	Missense
	c.5729A>T: p.Asn1910Ile	VUS	Missense
	c.7469T>C: p.Ile2490Thr	VUS	Missense
	c.956A>C: p.Asn319Thr	VUS	Missense
	c.3262C>T: p.Pro1088Ser	VUS	Missense
	c.4183G>T: p.Ala1395Ser	VUS	Missense