Table 1.
Mouse demographics and experimental parameters used to analyzed neuroanatomy in each experimental group
| Exp. group | Allele | Background | Sex | Age | WT | Mut | Imaging |
|---|---|---|---|---|---|---|---|
| Mecp2308 /y[B6,P200] | Mecp2tm1Hzo | C57BL/6J | M | 200 | 9 | 10 | 100G/cm,TR=325ms,TEeff=40ms,32 μm |
| Mecp2308 /x[B6,P200] | Mecp2tm1Hzo | C57BL/6J | F | 200 | 11 | 12 | 100G/cm,TR=325ms,TEeff=40ms,32 μm |
| Mecp2308 /308[B6,P200] | Mecp2tm1Hzo | C57BL/6J | F | 200 | 11 | 11 | 100G/cm,TR=325ms,TEeff=40ms,32 μm |
| Mecp2308 /y[B6,P60] | Mecp2tm1Hzo | C57BL/6J | M | 60 | 9 | 10 | 12G/cm,TR=2000ms,TEeff=42ms,56 μm |
| Mecp2308 /y[B6,P42] | Mecp2tm1Hzo | C57BL/6J | M | 42 | 5 | 5 | Weight calculations |
| Mecp2NULL/y[129,P60] | Mecp2tm1.1Bird | 129 /SvEvTac | M | 60 | 13 | 9 | 30G/cm,TR=350ms,TEeff=30ms,40 μm |
| Mecp2STOP/y[B6,P60] | Mecp2tm2Bird | C57BL/6J | M | 60 | 10 | 13 | 30G/cm,TR=350ms,TEeff=30ms,40 μm |
| Mecp2STOP/x[B6,P200] | Mecp2tm2Bird | C57BL/6J | F | 200 | 11 | 11 | 30G/cm,TR=350ms,TEeff=30ms,40 μm |
| Mecp2STOP/y[Hyb,P60] | Mecp2tm2Bird | C57 /CBA | M | 60 | 14 | 15 | 30G/cm,TR=350ms,TEeff=30ms,40 μm |
Mecp2 allele (Mecp2tm1Hzo, Mecp2tm1.1Bird, Mecp2tm2Bird), mouse background (C57BL/6J, 129/SvEvTac, C57/CBA hybrid), sex (male, female), age (days), sample size for WT and mutant mice (mut), gradient strength (G/cm), repetition time (TR), effective echo time (TEeff), and final image resolution (μm) for each experimental group. Experimental groups were named based on the Mecp2 allele, background and age