Fig. 5.

In utero SHS dysregulates the protein expression of DNMT3A, SERPINA1A, MAPK7, and PHF1 in male and female mice. a) Western blots show that DNMT3A and SERPINA1A were down-regulated, whereas MAPK7 and PHF1 were up-regulated in BALB/c male mice exposed in utero to SHS versus air-treated controls. b) Western blots show that SERPINA1A was down-regulated, whereas DNMT3A and MAPK7 were up-regulated in BALB/c female mice exposed in utero to SHS versus air-treated controls. c) Mean densitometry ± SEM results showing fold change of treated mice versus controls for the proteins analyzed