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. 2017 Jun 1;13(6):794–803. doi: 10.7150/ijbs.18969

Figure 3.

Figure 3

Low-dose berberine resensitized the DOX chemoresistance in MCF-7/hypoxial (A, B) Cell viability of low-dose berberine (2.5, 5 and 10 μM) combined with DOX in MCF-7/hypoxia cells for 48 h and 72 h treatment. Mean values ± SD, * P<0.05, cells treated with different concentrations of DOX vs. control group. # P <0.05, cells treated with different concentrations of DOX combined with 2.5 μM berberine vs. control group. ※ P <0.05, cells treated with different concentrations of DOX combined with 5 μM berberine vs. control group. ¤ P <0.05, cells treated with different concentrations of DOX combined with 10 μM berberine, vs. control group.