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. 2017 Feb 9;101(6):791–802. doi: 10.1002/cpt.589

Table 2.

Multiple regression analysis with forward selection for modeling P2Y12 reaction unit and H4 based on genotypes, interacting drugs, and age in 115 patients

Parameter Estimate Partial R2 Model R2 P value
Intercept 181.89 < 0.0001
rs2254638 in N6ANT1 ‐39.95 0.148 0.148 < 0.0001
PRU rs4244285 in CYP2C19 33.74 0.109 0.257 0.0001
CCB 140.61 0.051 0.308 0.0063
Male ‐23.71 0.044 0.352 0.0085
rs2487032 in ABCA1 ‐19.76 0.025 0.377 0.0441
Intercept ‐3.15 0.648
rs4244285 in CYP2C19 3.35 0.163 0.163 < 0.0001
H4 rs2254638 in N6ANT1 3.77 0.045 0.208 0.0166
Age 0.27 0.048 0.256 0.0106
rs12456693 in SLC14A2 3.35 0.027 0.283 0.0521

CCB, calcium channel blockers; PRU, P2Y12 reaction unit.

Rs4244285 in CYP2C19 is also known as CYP2C19*2.