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The different effector domain activation modes in fungal NLRs. The different domain architecture found in fungal NLR are given. The repeated boxes represent the superstructure-forming repeat domains (either ANK, TPR or WD), the central oval, the NBD (either NB-ARC or NACHT), the circle the effector domains (HeLo, HeLo-like, sesA, sesB, PNP-UDP phosphorylase, etc.).
