Table 1. Cell differentials in BAL after 3 days of tobacco smoke exposure in rats.
Vehicle (corn oil)
|
AUDA-nBE
|
AUDA-nBE + EETs
|
||||
---|---|---|---|---|---|---|
Filtered air | Tobacco smoke | Filtered air | Tobacco smoke | Filtered air | Tobacco smoke | |
Macrophages, % | 90.2 ± 2.9 | 48.7 ± 6.9†§ | 92.1 ± 3.2 | 62.9 ± 3.6†‡ | 93.4 ± 3.9 | 72.7 ± 6.8†‡§ |
Neutrophils, % | 9.0 ± 2.7 | 50.7 ± 6.8†§ | 7.3 ± 3.5 | 36.8 ± 3.2†‡ | 6.2 ± 3.7 | 27.1 ± 6.8†‡§ |
Lymphocytes, % | 0.80 ± 0.33 | 0.60 ± 0.23§ | 0.55 ± 0.30 | 0.25 ± 0.19‡ | 0.40 ± 0.16¶ | 0.25 ± 0.10‡ |
Eosinophils, % | 0.00 ± 0.00 | 0.05 ± 0.10 | 0.15 ± 0.19 | 0.10 ± 0.20 | 0.10 ± 0.20 | 0.00 ± 0.00 |
Data are presented as mean ± SD (n = 4). †, P < 0.05 compared with respective filtered air control. ‡, P < 0.05 compared with tobacco smoke plus vehicle. §, P < 0.05 compared with tobacco smoke plus AUDA-nBE. ¶, P < 0.05 compared with filtered air plus vehicle.