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. 2005 Jan 31;102(6):2117–2122. doi: 10.1073/pnas.0409726102

Fig. 1.

Fig. 1.

Comparisons of ICSS behavior, spontaneous locomotor activity, and performance in spatial tasks between WT and D1R-KO mice. (A) Self-stimulation screening. (a) Intensity–response curve. Vertical dashed bars indicate intensities used for plotting frequency–response curves in b.(b) Frequency–response curve. (B) Spontaneous locomotor activity. (C) Performance in DMT. Mean elapsed time per trial in DMT with predetermined distance criteria (DC) of 30, 50, and 80 cm per reward. (D and E) Performance in RRPST (D) and PLT (E). (a) Mean distance traveled per trial. (b) Mean number of rewards acquired per trial. Note that D1R-KO mice were retarded in acquisition of the PLT. All data are expressed as mean ± SEM. *, P < 0.05; **, P < 0.001 vs. WT group (Student's t test); †, P < 0.05 vs. same group on day 1 (Fisher's probable least-squares difference test).