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. Author manuscript; available in PMC: 2018 Jun 15.
Published in final edited form as: Cancer Res. 2017 May 16;77(12):3255–3267. doi: 10.1158/0008-5472.CAN-16-2458

Figure 2.

Figure 2

p62 promotes kidney cystogenesis and tumorigenesis in Tsc2f/f Ksp-CreERT2+ mice. A, Mice were treated with tamoxifen 63 mg/kg every other day for 5 days at 8–10 weeks and sacrificed 4 months later. Representative H&E images of Tsc2f/f Ksp-CreERT2+ p62+/+ and Tsc2f/f Ksp-CreERT2+ p62−/− kidneys. Scale bar, 100 um. B, Kidney areas were normalized to body weight. C, Kidney weights were normalized to body weight. n is number of kidneys analyzed. Data presented as the mean +/− 95% CI with *p<0.05, **p<0.01, ****p<0.0001.