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RYGB restricts meal size but not total food intake. (a) Total daily food intake, meal size and meal frequency of RYGB rats during 14-day ICV infusion of SHU9119. (b) Meal size, meal frequency and ingestion rate of liquid formula (Ensure) of rats at 2 weeks (2w) and 20 weeks (20w) after RYGB or sham surgery. *P<0.05, RYGB vs Sham, *P<0.05, SHU9119 vs Saline. Modified with permission from Zheng et al.,10 copyright American Physiological Association.
