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. 2017 Jun 28;357:j2813. doi: 10.1136/bmj.j2813

Table 3.

Intraobserver concordance of 118 pathologists’ interpretations of melanocytic skin biopsy lesions of the same case at phase 1 and phase 2 at least eight months apart*

Phase 1 diagnosis Phase 2 diagnosis (No of paired interpretations) Intraobserver concordance† % (95% CI)
Class I Class II Class III Class IV Class V Total
Class I 1155 188 119 27 17 1506 77 (73 to 80)
Class II 170 227 182 37 28 644 35 (31 to 39)
Class III 91 120 653 169 58 1091 60 (56 to 63)
Class IV 20 37 147 531 105 840 63 (59 to 67)
Class V 14 16 44 105 852 1031 83 (80 to 85)
Total 1450 588 1145 869 1060 5112 67‡ (65 to 69)

Numbers of diagnostic interpretations with intraobserver agreement are emboldened.

*Concordance rates are influenced by case composition, which included larger proportions of cases in classes II-V than would typically be encountered in practice.

†Denominator is phase 1 interpretations and numerator is phase 2 assessments that agreed with phase 1 interpretation. Does not include participants who reviewed glass slides in phase 1 and digital images in phase 2.

‡Average κ for intraobserver agreement across participants is 0.57.