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. 2017 May 23;18(6):1106. doi: 10.3390/ijms18061106

Figure 2.

Figure 2

PIK3CA inhibitor decreases CD26+ stem cell population in colorectal cancer cell line. (A) Representative flow cytometry plots after treatment with PIK3CA-inhibitor in HCT116, showing decrease of CD26+ cell population. Grey dotted line, isotype control. Black dashed line, untreated. Black solid line, treated with PIK3CA-inhibitor. CD26 positivity was defined by >99th percentile of CD26 intensity stained with isotype control. (B) Bar chart shows decrease in CD26+ population after PI3KCA-inhibitor treatment in HCT116 cell line. Bar = Mean + SEM. p = 0.048, n = 3, * p < 0.05.