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. 2017 May 25;18(6):1138. doi: 10.3390/ijms18061138
DNA Deoxyribonucleic acid
S phase Synthesis phase
ssDNA Single stranded DNA
DSB Double strand breaks
RPA Replication protein A
ATR Ataxia telangiectasia and Rad3-related protein
ROS Reactive oxygen species
dNTP Deoxynucleotide triphosphate
RNA Ribonucleic acid
RNase H Ribonuclease H
DDR DNA damage response
Chk1 Checkpoint kinase 1
MRN Mre11-Rad50-Nbs1
Chk2 Checkpoint kinase 2
H2AX H2A histone family member X
DDT DNA damage tolerance
LOH Loss of heterozygosity
CFS Common fragile site
ERFS Early replication fragile site
CNV Copy number variations
PARP1 Poly(ADP-ribose) polymerase 1
GOF p53 Gain of function p53
CTR Constant timing regions
TTR Timing transition regions
MEF Mouse embryonic fibroblasts
BrdU Bromodeoxyuridine
SNP Single nucleotide polymorphism
NHEJ Non-homologous end-joining
RUNX1 Runt-related transcription factor 1
p53 Tumor protein P53
RB1 Retinoblastoma 1
Bcl2 B-cell lymphoma 2
Rif1 Replication timing regulatory factor 1
MCM Minichromosome maintenance
ALL Acute lymphoblastic leukemia