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. 2017 May 30;18(6):1156. doi: 10.3390/ijms18061156

Figure 3.

Figure 3

Skeletal muscle mitochondrial performance of IR-IRS1dh mice. (A,B) Carnitine palmitoyl transferase activities (CPT I and II) measured in skeletal muscle homogenates. (C,D) Mitochondrial respiration determined in soleus muscle. pyr: pyruvate; glu: glutamate; mal: malate; succ: succinate. Pyruvate and glutamate were used as complex I substrates, succinate as complex II substrate. Columns represent mean values ± standard deviation; n: 4–6; * denotes significant differences between IR-IRS1dh mice compared to wt controls; * p < 0.05, ** p < 0.01.