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. 2017 May 30;18(6):1156. doi: 10.3390/ijms18061156
wt wild-type
IR insulin receptor
IRS-1 insulin receptor substrate-1
IR-IRS1dh mice insulin receptor (IR)+/–-insulin receptor substrate-1 (IRS-1)+/– double heterozygous mice
mo months
TCA tricarboxylic cycle
KO knockout
NAFLD non-alcoholic fatty liver disease
NASH non-alcoholic steatohepatitis
PPAR peroxisome proliferator-activated receptor
PGC1α peroxisome proliferator-activated receptor gamma coactivator 1-alpha