wt | wild-type |
IR | insulin receptor |
IRS-1 | insulin receptor substrate-1 |
IR-IRS1dh mice | insulin receptor (IR)+/–-insulin receptor substrate-1 (IRS-1)+/– double heterozygous mice |
mo | months |
TCA | tricarboxylic cycle |
KO | knockout |
NAFLD | non-alcoholic fatty liver disease |
NASH | non-alcoholic steatohepatitis |
PPAR | peroxisome proliferator-activated receptor |
PGC1α | peroxisome proliferator-activated receptor gamma coactivator 1-alpha |