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. 2017 Jun 1;18(6):1178. doi: 10.3390/ijms18061178

Figure 2.

Figure 2

The summary of the workflow in the identification of the novel bioactive agent is extraction, fractionation, then cell culture based test to evaluate the effects at cellular and molecular level of the bioactive extract and validation on animal models of the most relevant finding and the final step of a novel treatment is the clinical trials evaluation.