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. 2017 Jun 9;18(6):1232. doi: 10.3390/ijms18061232

Table 2.

In vitro cytotoxicity and inhibition of proliferation of cancer cell lines by T/Tn-specific lectins (ABL: Agaricus bisporus lectin; AAL: Agrocybe aegerita lectin; BfL: Bauhinia forficata lectin; GSA-IA4: Griffonia simplicifolia lectin; jacalin (Artocarpus integrifolia lectin); McL: Myrsine coriacea lectin; MCL: Momordica charantia lectin; ML-I, ML-II, ML-III: Mistletoe (Viscum album) lectins; PNA: peanut (Arachis hypogaea) agglutinin; ricin: Ricinus communis lectin; SBA: soybean (Glycine max) agglutinin; SRL: Sclerotium rolfsii lectin; riproximin (Ximenia americana).

Cancer Cell Line (H: Human, M: Mouse, R: Rat, Hamster: h) Lectin Toxicity Proliferation Inhibition Ref.
HT29 colon (H), MCF-7 breast (H) ABL - + [153]
HeLa (H), SW480 lymph node metastasis (H); SGC-7901, BGC-823 AAL + (M) + [35]
gastric cancer (H); MGC80-3 gastric adeno-carcinoma (H); HL-60
leukemia (H); S-180 sarcoma (M)
NCI-60 tumor cell line panel (H), LOX IMVI melanoma (H) BfL - + [46]
SK-MEL-28 melanoma (H), HT-144 melanoma (H), C32 melanoma GSA-IA4 + + [54,154]
(H), LS174t, SW1116 colon cancer (H)
A431 epidermoid carcinoma (H); HT29 colorectal carcinoma (H) Jacalin, PNA + + [155,156]
JAr choriocarcinoma (H); H3B hepato-carcinoma (H); B16
melanoma (M)
EAC Ehrlich ascites carcinoma; A549 lung carcinoma (H); CNE-1 MCL + + [157,158,159]
CNE-2 nasopharyngeal carcinoma (H)
BT20, BT549, MCF7, HS578T, HBL100, T47D breast cancer (H) ML-I, -II, -III + [141,160]
SK-Hep-1, SK-Hep-3B hepatocarcinoma (H)
HT-29 colon (H) McL + + [64]
G-361 melanoma (H); HepG2 hepatoma (H); SKGIIIa cervical Ricin + + [161,162]
carcinoma (H)
Raji, Daudi lymphoma cell lines (H); JAr choriocarcinoma (H); SBA + - [155,163]
H3B hepato-carcinoma (H); B16 melanoma (M)
HT-29 colon (H) SRL + + [164]
MCF7, MDA-MB231 breast carcinoma (H); U87-MG brain tumor (H) Riproximin + - [85]
HEp2 larynx (H); NCI-H460 lung (H); HT29 colon (H); PC3
prostate (H); SKW3, K562, BV173 leukemia (H)