Table 1.

The common culprit drugs in drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome.

Category	Drugs
Anti-convulsants	Carbamazepine [2,11,14,18], lamotrigine [2,11,14,18], phenobarbital [11,14,18], phenytoin [2,11,14,18], oxcarbazepine [11,14], gabapentin [37]
Anti-bacterial	Amoxicillin [11,14], ampicillin [14,18], azithromycin [38], levofloxacin [39], minocycline [11,14,18], piperacillin/tazobactam [40], vancomycin [11,14,18]
Anti-tuberculosis	Ethambutol [18,41], isoniazid [2,18,41], pyrazinamide [18,41], rifampin [18,41], streptomycin [11,18,41]
Anti-retroviral agents	Abacavir [11,18], nevirapine [11,14,18]
Anti-hepatitis C virus agents	Boceprevir [42,43], telaprevir [42,44]
Anti-pyretic/analgesics	Acetaminophen [45], diclofenac [2], celecoxib [11,18], ibuprofen [11,18]
Sulfonamides	Dapsone [2,11,14,18], sulfamethoxazole-trimethoprim [2,11,14,18], sulfasalazine [2,11,14,18]
Targeted therapeutic agents	Dorafenib [46], vismodegib [47], vemurafenib [48]
Others	Allopurinol [2,11,14,18], chinese herbal medicine [2], imatinib [11], mexiletine [11,18], omeprazole [11], strontium ranelate [11]

Bold characters highlight the most frequently reported culprit drugs in the literature, which are with a frequency of more than 10 cases ever reported.