Table 2.
The RegiSCAR scoring system for diagnosing DRESS syndrome.
| Items | Score | Comments | ||
|---|---|---|---|---|
| −1 | 0 | 1 | ||
| Fever ≧ 38.5 °C | N/U | Y | ||
| Enlarged lymph nodes | N/U | Y | >1 cm and ≧ 2 different areas | |
| Eosinophilia ≧ 0.7 × 109/L or ≧ 10% if WBC < 4.0 × 109/L | N/U | Y | Score 2, when ≧ 1.5 × 109/L or ≧ 20% if WBC < 4.0 × 109/L | |
| Atypical lymphocytosis | N/U | Y | ||
| Skin rash Extent > 50% of BSA Rash suggesting DRESS |
N |
N/U U |
Y Y |
Rash suggesting DRESS: ≧ 2 symptoms: purpuric lesions (other than legs), infiltration, facial edema, psoriasiform desquamation |
| Skin biopsy suggesting DRESS | N | Y/U | ||
| Organ involvement | N | Y | Score 1 for each organ involvement, maximal score: 2 | |
| Rash resolution ≧ 15 days | N/U | Y | ||
| Excluding other causes | N/U | Y | Score 1 if 3 tests of the following tests were performed and all were negative: HAV, HBV, HCV, Mycoplasma, Chlamydia, ANA, blood culture | |
ANA: anti-nuclear antibody; BSA: body surface area; HAV: hepatitis A virus; HBV: hepatitis B virus; HCV: hepatitis C virus; N: no; U: unknown; WBC: white blood cell; Y: yes.