Table 2.
FSH, LH and E2 levels in control subjects and POI patients with different miRNA polymorphic genotypes.
FSH (mIU/mL) Mean ± SD | LH (mIU/mL) Mean ± SD | E2 (pg/mL) Mean ± SD | ||||
---|---|---|---|---|---|---|
Control (227) | Case (143) | Control (227) | Case (143) | Control (227) | Case (143) | |
miR-938G>A | ||||||
GG | 8.16 ± 8.49 | 62.06 ± 13.31 | 3.36 ± 3.28 | 26.44 ± 10.55 | 25.43 ± 205.77 | 7.86 ± 2.50 |
GA | 7.36 ± 1.36 | 65.46 ± 24.83 | 2.44 ± 0.75 | 22.90 ± 12.96 | 35.83 ± 381.45 | 8.86 ± 3.87 |
AA | - | - | - | - | - | - |
p | 0.743 | 0.511 | 0.25 | 0.465 | 0.093 | 0.692 |
Data shown are the mean ± SD. Abbreviations: SD, standard deviation; FSH, follicle-stimulating hormone; LH, luteinizing hormone; E2, estradiol; POI, primary ovarian insufficiency.