Table 1.
Current Hydroxychloroquine (HCQ) clinical trials.
| Treatment | Condition | Phase | Trial Reference # at ClinicalTrials.gov |
|---|---|---|---|
| HCQ + sunitinib malate | Adult solid neoplasm | I | NCT00813423 |
| HCQ + vorinostat | Malignant solid tumor | I | NCT01023737 |
| HCQ + sirolimus or vorinostat | Advanced cancers | I | NCT01266057 |
| HCQ + Protein kinase B (Akt) inhibitor MK-2206 dihydrochloride (MK2206) | Advanced cancers | I | NCT01480154 |
| HCQ as a single agent | Estrogen receptor positive breast cancer | I | NCT02414776 |
| HCQ + gemcitabine | Advanced adenocarcinoma | I/II | NCT01506973 |
| HCQ + Interleukin 2(IL-2) | Renal cell carcinoma | I/II | NCT01550367 |
| HCQ + vorinostat | Colorectal cancer | I/II | NCT02316340 |
| HCQ + gemcitabine/carboplatin | Small cell lung cancer | I/II | NCT02722369 |
| HCQ + capecitabine | Pancreatic carcinoma | II | NCT01494155 |
| HCQ as a single agent | Prostate cancer | II | NCT00726596 |
| HCQ + Abraxane and gemcitabine | Pancreatic carcinoma | II | NCT01978184 |