Figure 4.
Comparison of ICG and DZ-1 imaging in orthotopic liver tumors. (A) Representative NIRF optical images of tumor sites by injection of DZ-1 (0.5 μmol/kg) in vivo. Scale bar: 20 μm. (B) Representative NIRF optical images of tumor sites by injection of ICG (10 μmol/kg) in vivo. However, there were more differences between the bioluminescence signal range and fluorescence in the tumor site in vitro. Scale bar: 20 μm. (C) A large area of carcinogenesis of liver identified by ICG (10 μmol/kg). The ex vivo signal range of bioluminescence in the organ is consistent with that of fluorescence.