Influence of cytokines on microtissue infiltrating CD3+CD8+ T lymphocyte subpopulations. Fig. 4 shows infiltrating CD3+CD8+ subpopulations into A549 (A) and Calu-6 (B) microtissues after 24 h. PMC = peripheral blood mononuclear cells, TCM = central memory T cells, TEM = effector memory T cells, TN = naïve T cells, TTE = terminal effector T cells. (n = 3) (*p < 0.05, **p < 0.005, ***p < 0.001).