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. Author manuscript; available in PMC: 2017 Jun 27.
Published in final edited form as: Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2011 Aug 10;3(6):620–646. doi: 10.1002/wnan.158

FIGURE 4.

FIGURE 4

Nanoshell immunoassay. (a) In concept, the nanoshell immunoassay is designed to enable rapid and accurate analyte concentration measurements in whole blood, while minimizing dependency on long sample handling and instrumentation typified by standard immunoassays.166 (b) Absorbance spectra of nanoshells prior to versus 30 min after analyte addition. Peak absorbance is estimated at 725 nm. A decrease in material extinction coefficient is observed as a result of clustering of the nanoshells.