Table 1.

miRNAs targeting different Autophagy-related pathways in phagophore induction.

Pathway	Target	Description	Autophagy	miRNA	Refs
Hypoxia	NDRG2	NDRG family member 2	activated	MIR301A/B	59
PI3K-AKT-MTOR	TGFBR2	transforming growth factor β receptor 2	inhibited	MIR19A/B-3p	138
	IGF1R	insulin like growth factor 1 receptor	activated	MIRLET7I	139,140
				MIR100
	PTEN	phosphatase and tensin homolog	activated	MIR21	117
	TSC1	tuberous sclerosis 1	inhibited	MIR451	52
	RHEB	Ras homolog enriched in brain	activated	MIR155	53,141
	RICTOR	RPTOR independent companion of MTOR complex 2	activated	MIR155	141,142
				MIR15A
				MIR16
	RPS6KB2	ribosomal protein S6 kinase B2	activated	MIR155	141
Ca2+-AMPK-MTOR	IP3K2	inositol 1,4,5-trisphosphate kinase 2	activated	Drosophila	57
				mir-14
	TRPM3	transient receptor potential cation subfamily M member 3	inhibited	MIR204	54
TP53	TIGAR	TP53 induced glycolysis regulatory phosphatase	activated	MIR144	143
	CDKN1A	cyclin dependent kinase inhibitor 1A	activated	MIR182	144
	DRAM1	DNA damage regulated autophagy modulator 1	inhibited	MIR199A-5p	145
	SIRT1	sirtuin 1	inhibited	MIR140–3p	55,146,147
				MIR212
				MIR34A
	HMGB1	high mobility group box 1	inhibited	MIR129–5p	148–153
				MIR141
				MIR218
				MIRLET7F
				MIR22
	HMGB2	high mobility group box 2	inhibited	MIR23B-3p	154
MAPK1/ERK2-MAPK3/ERK1	DUSP4/5	dual specificity phosphatase 4/5	activated	MIR26A	155
Translational factors	FOXO3	forkhead box O3	inhibited	MIR182	118,156
				MIR212/132
	TFAP2A	transcription factor AP-2 α	inhibited	MIR638	157
	STAT3	signal transducer and activator of transcription 3	inhibited	MIR17–5p	70
Mitophagy	BNIP3L	BCL2 interacting protein 3 like	inhibited	MIR137	158
	FUNDC1	FUN14 domain containing 1	inhibited	MIR137	158
	UCP2	uncoupling proteins 2	inhibited	MIR214	159
CDKN1B -CDK2-MTOR	CDKN1B	cyclin-dependent kinase inhibitor 1B	inhibited	MIR221	119
Hedgehog	Gas1	growth arrest specific 1	activated	MIR148A	160
Others	PSME4	proteasome activator subunit 4	inhibited	MIR29B	161
	ARC	activity regulated cytoskeleton associated protein	activated	MIR325	162
	UBQLN1	ubiquilin 1	inhibited	MIR200C	163