Table 1.

Comparison of number of fibroblasts immunostained for antibodies to LR8 and SMA in normal and fibrotic human tissue sections^*.

Tissue	LR8negative		LR8positive@		LR8 positive and SMApositive
	Normal	fibrotic	Normal	fibrotic	Normal	fibrotic
Liver	2±1	20±2	43±10#	60±25#	5±2**	36±9**
Lung	0	0	30±3#	38±2#	8±4**	23±9**
Kidney	15±5	11±1	19±7#	17±6#	1±1**	9±2**

^*Cells were quantified in three fields each of normal and fibrotic tissue sections. Data are presented as mean±SD.

^@Percentage of LR8 positive cells in normal liver, lung and kidney were 96±2, 100±0 and, 55±12, respectively. Corresponding values for fibrotic tissues were 74±11, 100±0 and 61±7, respectively.

^#Number of LR8 positive cells in normal tissues vs. fibrotic tissues: t=1.4826, p=0.2348. (Number of LR8 positive cells in normal liver vs. fibrotic liver: t=1.0936, p=0.3356. Number of LR8 positive cells in normal lung vs. fibrotic lung: t= 3.8431, p=0.0184. Number of LR8 positive cells in normal kidney vs. fibrotic kidney: t=0.3757, p=0.7262).

^**Number of LR8 and SMA positive cells in normal tissues vs. fibrotic tissues: t=4.478, p=0.0208. (Number of LR8 and SMA positive cells in normal liver vs. fibrotic liver: t=5.8239, p=0.0043. Number of LR8 and SMA positive cells in normal lung vs. fibrotic lung: t=2.6379, p=0.0577. Number of LR8 and SMA positive cells in normal kidney vs. fibrotic kidney: t=6.1968, p= 0.0034).