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. 2005 Feb 3;24(3):623–634. doi: 10.1038/sj.emboj.7600523

Figure 1.

Figure 1

CycD/Cdk4 requires mRpL12 to drive growth in the Drosophila eye. (A) SEM images at × 500 magnification. Genotypes: GMR-Gal4/+; +/+ (left), GMR-Gal4 UAS-CycD UAS-Cdk4/+;+/+ (second from left), GMR-Gal4/+; Df(3L)Scf-R6/+ (third from left) and GMR-Gal4 UAS-CycD UAS-Cdk4/+; Df(3L)Scf-R6/+ (right). Scale bar, 20 μm. (B) Break points of the deficiencies used. ‘+' indicates suppression of the overgrowth phenotype whereas ‘−' indicates no change as compared to a wild-type background. (C) SEM at × 120 magnification. CycD/Cdk4 is driven from the GMR-Gal4 driver. ‘+/+' indicates precise excisions of P{PZ}10534. Scale bar: 100 μm. All flies in A and C are females, reared at 22.5°C. (D) Genomic locus of MRPL12. The lethal P-element (P{PZ}10534) insertion into the 5′UTR of MRPL12 is indicated. The 3′UTR of CG5008 ends 294 bp upstream of MRPL12, and the 5′UTR of CG13313 starts 600 bp downstream of MRPL12.