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Dose reduction
| Dose reduction | 6M group (n = 642) | 12M group (n = 636) | ||
|---|---|---|---|---|
| Overall (n = 636) | During cycles 1–8 (n = 636) | During cycles 9–16 (n = 417) | ||
| n (%) | n (%) | n (%) | n (%) | |
| (−) | 401 (62.5%) | 330 (51.9%) | 379 (59.6%) | 308 (73.9%) |
| (+) | 241 (37.5%) | 306 (48.1%) | 257 (40.4%) | 109 (26.1%) |
