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. 2017 Jun 11;13:1744806917714342. doi: 10.1177/1744806917714342

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© The Author(s) 2017

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 4. — Slack deletion alters synaptic responses to LOX in inhibitory but not excitatory neurons. (a) Average EPSC amplitude in response to LOX (50 µM) for inhibitory (circles) and excitatory (squares) WT neurons. Inset representative traces before (1, black) and after (2, red) LOX for inhibitory (above) and excitatory (below) neurons, p < 0.01. (b) PPR for WT inhibitory neurons before and after LOX. (c) Same parameters as (a) for Slack KO, p < 0.01. Inset representative traces before (1, black) and after (2, red) LOX for excitatory (above) and inhibitory (below). (d) PPR for Slack KO inhibitory neurons before and after LOX (p < 0.05). (e) Basal PPR for WT and KO inhibitory neurons. (f) Basal PPR for WT and KO excitatory neurons (p < 0.05).

WT: wildtype; KO: knockout; LOX: loxapine.