Skip to main content
. 2017 Jun 9;57(1):156–165. doi: 10.1007/s12020-017-1316-3

Table 2.

AEs (regardless of study drug relationship) occurring in ≥10% of the 162 patients who received pasireotide

Preferred term Overall population (N = 162) Patients reaching month 60 (N = 16)
Grades 3/4 All grades Grades 3/4 All grades
n (%) n (%) n (%) n (%)
Diarrhoea 5 (3.1) 95 (58.6) 0 7 (43.8)
Nausea 4 (2.5) 87 (53.7) 2 (12.5) 11 (68.8)
Hyperglycaemia 21 (13.0) 67 (41.4) 2 (12.5) 9 (56.3)
Cholelithiasis 3 (1.9) 53 (32.7) 1 (6.3) 8 (50.0)
Headache 3 (1.9) 50 (30.9) 1 (6.3) 7 (43.8)
Abdominal pain 4 (2.5) 41 (25.3) 1 (6.3) 8 (50.0)
Diabetes mellitus 14 (8.6) 36 (22.2) 2 (12.5) 8 (50.0)
Fatigue 3 (1.9) 36 (22.2) 1 (6.3) 8 (50.0)
Nasopharyngitis 0 24 (14.8) 0 6 (37.5)
Alopecia 0 21 (13.0) 0 3 (18.8)
Hypercholesterolaemia 0 20 (12.3) 0 4 (25.0)
Abdominal pain upper 0 19 (11.7) 0 6 (37.5)
Asthenia 4 (2.5) 19 (11.7) 0 3 (18.8)
Dizziness 2 (1.2) 19 (11.7) 0 3 (18.8)
ALT increased 4 (2.5) 18 (11.1) 0 2 (12.5)
Gamma-glutamyltransferase increased 6 (3.7) 18 (11.1) 0 2 (12.5)
HbA1c increased 1 (0.6) 18 (11.1) 0 1 (6.3)
Hypertension 0 18 (11.1) 0 2 (12.5)
Hypoglycaemia 3 (1.9) 18 (11.1) 0 3 (18.8)
Decreased appetite 0 17 (10.5) 0 2 (12.5)
Myalgia 1 (0.6) 17 (10.5) 1 (6.3) 8 (50.0)

ALT alanine aminotransferase