Figure 6.

RNAi depletion of p68 does not affect NF-κB activation by TNFα. (A) Induction of NF-κB activity by TNFα in cells transfected with p68 or control siRNA, compared with untransfected cells, as determined by measuring relative luciferase activity. The luciferase activity of untransfected cells, which had not been treated with TNFα, was taken as 1. (B) β-Galactosidase activity in cells. The levels shown represent values relative to that of untransfected and untreated cells, which were taken as 1. Graphs represent the average values from two independent experiments, and reactions were, in each case, performed in duplicate.