Table 2.
Differences between serum FAs concentrations (mg/l) in obese and non-obese psoriatic patients and the control group
| Fatty acid | Psoriasis BMI <30 (n = 58) |
Psoriasis BMI ≥30 (n = 27) |
Control (n = 32) |
|---|---|---|---|
| Myristic (14:0) | 25.3 (19.7–37.4)* | 34.8 (22.1–47.2) | 34.8 (23.5–56.5) |
| Palmitic (16:0) | 761.2 (706.2–982.2) | 882.8 (802.2–1162.4)# | 755.9 (707.9–959.2) |
| Palmitoleic (16:1n–7) | 97.6 (73.3–154.0)* | 124.9 (94.3–155.0)** | 75.7 (55.4–101.6) |
| Stearic (18:0) | 233.8 (199.1–268.9) | 253.9 (212.2–295.9) | 250.5 (233.2–278.4) |
| Oleic (18:1n9c) | 811.9 (717.9–1045.5) | 920.5 (807.9–1092.3)* | 787.1 (702.8–881.4) |
| Linoleic (18:2n-6) | 964 (840.5–1066.8)*** | 971.9 (897.2–1117.1)* | 1102.5 (1013.5–1229.9) |
| Arachidic (20:0) | 7.3 (6.4–8.8)*** | 8.5 (7.0–8.9)** | 9.9 (8.1–11.5) |
| α-Linolenic (18:3n-3) | 18.5 (16.0–26.5)*** | 22.4 (19.1–27.4)* | 29.8 (23.1–37.1) |
| Behenic (22:0) | 14.6 (13.2–18.0)*** | 15.8 (13.9–18.7)** | 19.5 (16.9–22.5) |
| Arachidonic (20:4n-6) | 249.5 (214.5–288.1)* | 266 (230.4–306.6) | 285.7 (243.5–315.2) |
| Lignoceric (24:0) | 10.6 (8.8–12.5)*** | 10.7 (9.5–11.7)*** | 14.2 (12.1–17.0) |
| Eicosapentaenoic (20:5n-3) | 30.5 (20.9–45.0)** | 36.6 (22.8–49.9) | 48 (36.4–63.4) |
| Nervonic (24:1n-9) | 43.4 (37.4–49.9) | 41.4 (35.1–47.0) | 45 (41.6–50.8) |
| Docosahexaenoic (22:6n-3) | 64.7 (53.2–82.3)* | 76 (58.9–93.9) | 80.8 (67.6–89.9) |
| Total FA | 3417.2 (2991.4–4006.1) | 3613.1 (3395.4–4228.0) | 3556.1 (3250.8–4147.2) |
| n-3 PUFA | 120.3 (95.3–148.9)*** | 127.8 (110.6–171.1) | 158.7 (135.7–185.7) |
| n-6 PUFA | 1243.3 (1064.6–1367.2)*** | 1233.3 (1119.2–1375.6)* | 1411.3 (1264.9–1529.1) |
| n-6/n-3 ratio | 10.3 (8.4–12.2) | 9.3 (7.2–11.3) | 9.1 (7.2–10.4) |
| %SFA | 32 (31.2–32.9) | 33.3 (31.7–34.3)**,# | 31.3 (30–32.8) |
| %MUFA | 28.9 (26.3–31.6)*** | 30.4 (28.6–32.7)*** | 25.5 (23.4–27.1) |
| %PUFA | 39.1 (36.2–41.9)*** | 36.1 (31.9–38.8)***, # | 43.2 (40.6–45.7) |
| SFA/UFA | 0.47 (0.45–0.49) | 0.50 (0.46–0.52)***, ## | 0.45 (0.43–0.49) |
Data are shown as median and quartiles (Q1 first quartile, Q3 third quartile)
Significant differences between psoriatic groups and controls are shown as: * p < 0.05; ** p < 0.01; *** p < 0.001. The differences between the obese and non-obese psoriatic patients as: # p < 0.05; ## p < 0.01