Table 3.
Effect of OLE on 24-h ambulatory blood pressure data
| Variable (mmHg) | OLE | Control | OLE versus control mean difference (SD) | n § | p ‡ | ||||
|---|---|---|---|---|---|---|---|---|---|
| Baseline | End | Mean change (SD) | Baseline | End | Mean change (SD) | ||||
| 24-h SBP | 134.75 (±11.67) | 133.27 (±9.45) | −1.49 (±7.56) | 132.59 (±10.28) | 134.45 (±10.92) | 1.84 (±7.90) | −3.33 (±10.81) | 45 | 0.045 |
| 24-h DBP | 80.35 (±8.65) | 80.03 (±8.09) | −0.20 (±5.65) | 79.10 (±8.11) | 81.25 (±8.91) | 2.22 (±6.32)* | −2.42 (±7.61) | 45 | 0.039 |
| Day SBP | 139.69 (±12.28) | 137.45 (±10.21) | −2.25 (±8.01) | 137.49 (±10.25) | 139.22 (±11.30) | 1.70 (±7.13) | −3.95 (±11.48) | 44 | 0.027 |
| Day DBP | 83.71 (±8.86) | 83.29 (±8.12) | −0.50 (±6.13) | 82.32 (±8.40) | 84.97 (±8.95) | 2.50 (±6.50)* | −3.00 (±8.54) | 44 | 0.025 |
| Night SBP | 115.58 (±10.22) | 115.78 (±9.67) | 0.16 (±10.44) | 112.89 (±9.98) | 116.16 (±11.52) | 3.19 (±9.68)* | −3.02 (±14.41) | 43 | 0.176 |
| Night DBP | 67.66 (±8.53) | 67.43 (±7.52) | −0.09 (6.81) | 66.24 (±7.43) | 67.81 (±7.95) | 1.47 (±6.12) | −1.56 (±9.69) | 43 | 0.298 |
Data points are mean ± SD
OLE olive leaf extract, SBP systolic blood pressure, DBP diastolic blood pressure
* End value was significantly different from baseline value, paired Student’s t tests
§Missing data points result predominantly from unreturned measurements by volunteers
‡Values derived from paired Student’s t tests comparing OLE mean change values with control mean change values