Table 2.

Integrative analyses of plasma proteomics and metabolomics results to show the lipid, carbohydrate, and protein metabolism in HS dairy cows

Item	Proteomics (Min et al. 2016a)	Metabolomics (Tian et al. 2015)	Metabolic response
Lipid metabolism	Phosphatidylcholine-sterol acyltransferase, apolipoprotein B-100, apolipoprotein A-I, and apolipoprotein A-II ↓	Phosphatidylcholine (PC) (16:0/14:0), PC (14:1/18:3), PC (12:0/22:2), PC (15:1/18:2), PC (20:2/12:0), and PC (18:1/18:3) ↓	Lipolysis ↓
Carbohydrate metabolism	Lactate dehydrogenase ↑	Lactate ↑	Glycolysis ↑
Protein metabolism	Aminoacylase-1 ↑	Proline, glycine, threonine, isoleucine, and arginine ↑	Catabolism of amino acids ↑