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. 2017 Apr 30;96(7):1113–1120. doi: 10.1007/s00277-017-2994-x

Table 2.

Molecular response (IWG-MRT/ELN criteria)a

Ruxolitinib-randomized (n = 102) Ruxolitinib crossover (n = 94) BAT (n = 85)
CMR, n (%) 2 (2.0) 1 (1.1) 0
 Median time to CMR (weeks) 143.4 123.0 N/A
PMR, n (%) 33 (32.4) 20 (21.3) 1 (1.2)
 Median time to PMR (weeks) 112.0 91.9 32.0

BAT best available therapy, CMR complete molecular response, IWG-MRT/ELN International Working Group–Myeloproliferative Neoplasms Research and Treatment/European LeukemiaNet, N/A not applicable, PMR partial molecular response

aAmong patients with a positive JAK2 p.V617F mutation at baseline and ≥1 postbaseline assessment of allele burden