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Final percentage reduction from baseline in JAK2 p.V617F allele burden and spleen volume
| Ruxolitinib-randomized | Ruxolitinib crossover | |||
|---|---|---|---|---|
| JAK2 p.V617F allele burden reduction | ≥20% (n = 52) | <20% (n = 47) | ≥20% (n = 32) | <20% (n = 60) |
| Spleen volume reduction, n (%) | ||||
| ≥35% | 45 (86.5) | 18 (38.3) | 25 (78.1) | 20 (33.3) |
| <35% | 7 (13.5) | 29 (61.7) | 7 (21.9) | 40 (66.7) |
Only patients with baseline and postbaseline values for both spleen volume and allele burden were included
