Table 1.
References | Country, study design | Sample size (male/female) | Age (years) | TA duration (months) | MMF therapya (months) | Other immunosuppressive drugs before MMF (n) |
---|---|---|---|---|---|---|
Goel et al. [5] | India, retrospective | 21b (2/19) | Mean ± SD: 31.9 ± 13.8 | Mean ± SD: 35.5 ± 28.4 Range:1–120 |
Mean ± SD: 9.6 ± 6.4 | Azathioprine (10) |
Shinjo et al. [6] | Brazil, prospective | 10c (3/7) | Mean ± SD: 29.9 ± 8.9 Range: 18–40 |
Mean ± SD: 57.5 ± 65.8 | Mean ± SD: 23.3 ± 12.1 | Methotrexate (4)d,e
Azathioprine (2)d Chlorambucil (1)e |
TA Takayasu’s arteritis, MMF mycophenolate mofetil
aMycophenolate mofetil as an alternative immunosuppressive drug accompanying steroids in controlling TA disease activity
bOne patient was not used to evaluate efficacy because of a skin rash, and 11 patients were on steroids alone before MMF
cOne patient was not used to evaluate efficacy due to a severe headache, and five patients were on steroids alone before MMF
dOne received methotrexate + azathioprine
eOne received chlorambucil + methotrexate