Table 1.

Pathways significantly (p < 0.1) upregulated and downregulated in CV7(L) as determined by KOBAS pathway analysis

Pathways upregulated in CV7(L)	Pathways downregulated in CV7(L)
Ribosome	Ubiquitin-mediated proteolysis
Biosynthesis of secondary metabolites	Cell cycle—yeast
Oxidative phosphorylation	MAPK signalling pathway—yeast
Metabolic pathways	Regulation of autophagy
Cysteine and methionine metabolism	Nucleotide excision repair
Lysine biosynthesis	Mismatch repair
Valine, leucine and isoleucine biosynthesis	Meiosis—yeast
Phenylalanine, tyrosine and tryptophan biosynthesis	Proteasome
Alanine, aspartate and glutamate metabolism	DNA replication
Ubiquinone and other terpenoid-quinone biosynthesis	Endocytosis
Terpenoid backbone biosynthesis	Natural killer cell-mediated cytotoxicity
Peroxisome	SNARE interactions in vesicular transport
Sulphur metabolism	Folate biosynthesis
Aminoacyl-tRNA biosynthesis
mRNA surveillance pathway
Tyrosine metabolism
Phenylalanine metabolism