Fig. 1.

Examples of abdominal PET/CT and SPECT/CT images including normal liver, liver metastases and spleen for reference. Left column: low peptide dose [⁶⁸Ga]-ABY-025-PET/CT at 1, 2, and 4 hours after injection. Middle column: high peptide dose [⁶⁸Ga]-ABY-025-PET/CT at corresponding time points in the same patient. Right column (other patient): [¹¹¹In]-ABY-025--SPECT/CT at 4, 24, and 48 hours after injection. The PET colour scale is thresholded at SUV 32. The SPECT images are corrected for the decay of ¹¹¹In to represent uptake and the colour scale arbitrarily normalised. Arrows indicate a liver metastasis of breast cancer in each of the two patients. Examples of dual spleen VOI:s (spherical) and single slice circular ROI are shown in yellow (first row PET images). ⁶⁸Ga LD and ⁶⁸Ga HD stand respectively for low and high peptide content [⁶⁸Ga]-ABY-025. ¹¹¹In stands for [¹¹¹In]-ABY-025