Table 2.

Coefficient of variation (%CV) for tissue measurements with [⁶⁸Ga]-ABY-025 PET in relation to injected peptide mass and time after tracer injection, and [¹¹¹In]-ABY-025-SPECT in relation to time after tracer injection

	[68Ga]-ABY-025 PET						[111In]-ABY-025 SPECT
	Low peptide dose			High peptide dose
Reference tissue	1 h %CV	2 h %CV	4 h %CV	1 h %CV	2 h %CV	4 h %CV	4 h %CV	24 h %CV	48 h %CV
Spleen (VOI)	17*	18*	28**	16*	17**	19***	19*	31*	28*
Spleen (ROI)	21*	23**	27*	20**	18**	22***
Lung (ventral)	42	39*	38***	33*	35**	35***	28	28*	31*
Lung (hilus level)	45	40	34***	28*	32**	29***	39	40*	45*
Lung (dorsal)	37	33*	31***	25*	30**	32***	32	38*	37*
Liver	30*	34*	30**	31*	33**	27***	31*	28*	27*
Kidney	20	19*	17*	16*	18*	26**	15	19*	18*
Shoulder muscle	25	31	20*	29*	19*	30*	18*	21*	24*
Dorsal spine muscle	53*	60**	35*	57*	52*	44**	10*	19*	24*
Gluteus muscle	40	38	35	35	35	35**
Blood pool, heart	36	25*	14**	25*	18*	16*	15*	31*	19*
Blood pool, aorta	41	33	25*	37	33	28***
Visceral fat	58*	34*	71***	53*	57	63***
Subcutaneous fat	49	40	44*	48	48	43**	12*	22*	19*
Cerebellum	30*	30**	40**	21*	24*	43**
Cerebrum	28	21*	25*	26*	26*	33**

P-values for correlation of HER2-diagnostics with T/R and the specified tissue as reference, against biopsy analysis results for each time and dose combination coded as: * = P < 0.05, ** = P < 0.01, *** = P < 0.005