Table 3.
Reproducibility of tumour to reference tissue ratios (T/R) for [68Ga]-ABY-025 PET high peptide dose at 2 hours after injection using various reference tissues
| Reference tissue | Test, T/R | Retest, T/R | P | Repeatability coefficient (absolute) | Repeatability coefficient (relative) |
|---|---|---|---|---|---|
| Spleen (dual VOI) | 8.5 ± 6.7 | 8.1 ± 7.0 | 0.74 | 2.90 | 14.6% |
| Spleen (simple ROI) | 8.4 ± 6.6 | 8.6 ± 6.8 | 0.91 | 3.34 | 18.7% |
| Lung (ventral) | 20.4 ± 18.6 | 20.1 ± 17.8 | 0.85 | 5.34 | 20.1% |
| Lung (hilus level) | 20.9 ± 17.4 | 21.0 ± 17.0 | 0.91 | 5.01 | 16.4% |
| Lung (dorsal) | 16.0 ± 12.0 | 15.8 ± 13.0 | 0.80 | 3.81 | 17.2% |
| Liver | 3.2 ± 3.0 | 2.7 ± 2.1 | 0.91 | 1.72 | 24.0% |
| Kidney | 0.42 ± 0.41 | 0.39 ± 0.36 | 0.74 | 0.222 | 28.2% |
| Blood pool (heart) | 5.6 ± 4.6 | 5.4 ± 3.9 | 0.97 | 2.06 | 12.3% |
| Blood pool (aorta) | 8.1 ± 6.0 | 8.8 ± 6.8 | 0.80 | 3.40 | 24.4% |
| Shoulder muscle | 27.9 ± 25.3 | 25.0 ± 19.5 | 0.97 | 12.2 | 13.2% |
| Dorsal spine muscle | 31.0 ± 22.2 | 29.8 ± 20.2 | 0.80 | 11.4 | 23.1% |
| Gluteal muscle | 25.5 ± 22.5 | 25.5 ± 21.1 | 0.91 | 5.26 | 16.9% |
| Visceral fat | 59.1 ± 75.3 | 45.3 ± 57.9 | 0.48 | 34.3 | 25.9% |
| Subcutaneous fat | 74.9 ± 51.3 | 78.2 ± 48.8 | 0.97 | 18.6 | 29.7% |
| Cerebellum | 122 ± 118 | 84.9 ± 66.1 | 0.53 | 135 | 26.9% |
| Cerebrum | 246 ± 208 | 460 ± 792 | 0.91 | 1597 | 114% |