Table 2.
Baseline, surgical and histopathologic characteristics of 2077 patients treated with primary gastrectomy for cancer
| Characteristic | All (N = 2077) | <5 weeks (n = 772) | 5–8 weeks (n = 727) | >8 weeks (n = 578) | p | ||||
|---|---|---|---|---|---|---|---|---|---|
| n | (%) | n | (%) | n | (%) | n | (%) | ||
| Baseline characteristics | |||||||||
| Age, year, mean (±SD) | 73.5 | (±10.1) | 73.2 | (10.4) | 74.6 | (8.9) | 72.3 | (11.1) | <0.001 |
| Gender | 0.345 | ||||||||
| Male | 1253 | (60) | 461 | (37) | 429 | (34) | 363 | (29) | |
| Female | 824 | (40) | 311 | (38) | 298 | (36) | 215 | (26) | |
| Malignancy history | 0.393 | ||||||||
| No | 1745 | (84) | 659 | (38) | 608 | (35) | 478 | (27) | |
| Yes | 332 | (16) | 113 | (34) | 119 | (36) | 100 | (30) | |
| Tumor differentiation | 0.008 | ||||||||
| Good to moderate | 582 | (34) | 212 | (31) | 197 | (33) | 173 | (40) | |
| Poor to undifferentiated | 1131 | (66) | 467 | (69) | 404 | (67) | 260 | (60) | |
| Missing | 364 | 93 | 126 | 145 | |||||
| cT stage | <0.001 | ||||||||
| T1 | 139 | (19) | 24 | (17) | 37 | (27) | 78 | (56) | |
| T2 | 347 | (48) | 120 | (35) | 133 | (38) | 94 | (27) | |
| T3 | 150 | (21) | 57 | (38) | 50 | (33) | 43 | (29) | |
| T4a | 84 | (12) | 45 | (54) | 24 | (29) | 15 | (18) | |
| Tx | 1357 | 526 | 483 | 348 | |||||
| cN stage | <0.001 | ||||||||
| N0 | 1326 | (77) | 440 | (33) | 483 | (36) | 403 | (30) | |
| N+ | 387 | (23) | 181 | (47) | 136 | (35) | 70 | (18) | |
| Nx | 364 | 151 | 108 | 105 | |||||
| Year of diagnosis | <0.001 | ||||||||
| 2006–2008 | 934 | (45) | 426 | (46) | 308 | (33) | 200 | (21) | |
| 2009–2011 | 608 | (29) | 187 | (31) | 220 | (36) | 201 | (33) | |
| 2012–2014 | 535 | (26) | 159 | (30) | 199 | (37) | 177 | (33) | |
| Referral status | <0.001 | ||||||||
| Diagnosis in treatment hospital | 1657 | (86) | 674 | (41) | 585 | (35) | 398 | (24) | |
| Diagnosis in other hospital | 262 | (14) | 60 | (23) | 81 | (31) | 121 | (46) | |
| Missing | 158 | 38 | 61 | 59 | |||||
| Treatment and histopathologic characteristics | |||||||||
| Surgical type | 0.008 | ||||||||
| Distal gastrectomy | 1435 | (69) | 545 | (38) | 501 | (35) | 389 | (27) | |
| Total gastrectomy | 607 | (29) | 206 | (34) | 215 | (35) | 186 | (31) | |
| Multiorgan surgery | 35 | (2) | 21 | (60) | 11 | (31) | 3 | (9) | |
| Surgical approach | 0.002 | ||||||||
| Open | 1908 | (94) | 728 | (38) | 671 | (35) | 509 | (27) | |
| Laparoscopic | 129 | (6) | 33 | (26) | 45 | (35) | 51 | (40) | |
| Missing | 40 | 11 | 11 | 18 | |||||
| Radicality | 0.003 | ||||||||
| R0 | 1689 | (85) | 595 | (35) | 599 | (35) | 495 | (29) | |
| R1–2 | 291 | (15) | 126 | (43) | 106 | (36) | 59 | (20) | |
| Rx | 97 | 51 | 22 | 24 | |||||
| pT stage | <0.001 | ||||||||
| T1 | 454 | (22) | 89 | (20) | 156 | (34) | 209 | (46) | |
| T2 | 321 | (16) | 104 | (32) | 121 | (38) | 96 | (30) | |
| T3 | 747 | (36) | 321 | (43) | 259 | (35) | 167 | (22) | |
| T4a | 489 | (24) | 234 | (48) | 166 | (34) | 89 | (18) | |
| T4b | 55 | (3) | 23 | (42) | 21 | (38) | 11 | (20) | |
| Tx | 11 | 1 | 4 | 6 | <0.001 | ||||
| pN stage | |||||||||
| N0 | 995 | (48) | 291 | (29) | 346 | (35) | 358 | (36) | |
| N1 | 347 | (17) | 137 | (39) | 127 | (37) | 83 | (24) | |
| N2 | 336 | (16) | 146 | (43) | 121 | (36) | 69 | (21) | |
| N3 | 390 | (19) | 193 | (49) | 130 | (33) | 67 | (17) | |
| Nx | 9 | 5 | 3 | 1 | |||||
| pM stage | 0.162 | ||||||||
| M0 | 2003 | (96) | 737 | (37) | 707 | (35) | 559 | (28) | |
| M1 | 74 | (4) | 35 | (47) | 20 | (27) | 19 | (26) | |
| Curative intent | 0.035 | ||||||||
| Yes | 1946 | (94) | 713 | (37) | 687 | (35) | 546 | (28) | |
| No | 120 | (6) | 58 | (48) | 36 | (30) | 26 | (22) | |
| Missing | 11 | 1 | 4 | 6 | |||||
| 90-day mortality | 240 | (12) | 94 | (12) | 68 | (9) | 78 | (13) | 0.053 |
| Adjuvant therapy | 0.043 | ||||||||
| No | 1993 | (96) | 730 | (37) | 704 | (35) | 559 | (28) | |
| Chemotherapy | 28 | (1) | 11 | (39) | 6 | (21) | 11 | (39) | |
| Radiotherapy | 1 | (<1) | 1 | (100) | 0 | (0) | 0 | (0) | |
| Chemoradiation | 55 | (3) | 30 | (55) | 17 | (31) | 8 | (15) | |