Table 3.
Univariable and multivariable Cox proportional hazard analysis on influence of WT on risk of death in patients treated with neoadjuvant chemotherapy followed by gastrectomy or primary gastrectomy for cancer
Characteristic | Univariable | Multivariablea | ||
---|---|---|---|---|
HR (95% CI) | p | HR (95% CI) | p | |
Neoadjuvant treatment | ||||
WT ≤5 weeks | Ref | – | Ref | – |
WT 5–8 weeks | 0.79 (0.67–0.94) | 0.008* | 0.82 (0.66–1.02) | 0.068 |
WT >8 weeks | 0.80 (0.62–1.05) | 0.106 | 0.85 (0.59–1.21) | 0.354 |
Additional week WT | 0.97 (0.94–1.01) | 0.057 | 0.96 (0.92–1.00) | 0.078 |
Surgery only | ||||
WT ≤5 weeks | Ref | – | Ref | – |
WT 5–8 weeks | 0.86 (0.76–0.98) | 0.018* | 0.92 (0.81–1.05) | 0.200 |
WT >8 weeks | 0.75 (0.65–0.86) | <0.001* | 0.95 (0.79–1.08) | 0.314 |
Additional week WT | 0.97 (0.96–0.99) | <0.001* | 0.99 (0.98–1.01) | 0.264 |
CI confidence interval, HR hazard ratio, WT waiting time
* Statistically significant (p < 0.05)
aAdjusted for baseline characteristics: age, gender, malignancy history, tumor differentiation, cT stage, cN stage, year of diagnosis, and referral status