Table 1B. Demographics, GIST patients.
n = 20 | |
---|---|
Gender (M:F) | 13:7 |
Age (median, range) | 54 (40–75) |
ECOG (median, range) | 0 (0–1) |
Prior treatments (median, range) | 3 (1–8) |
Primary site | |
Gastric | 8 |
Small bowel | 12 |
Mutationsa | |
KIT exon 9 (502_503 duplication) | |
KIT exon 9 (S501) | |
KIT exon 9 (6bp deletion) and KIT exon 17 (D820Y) | |
KIT exon 9 (6bp insertion) and KIT exon 14 (N680K) | |
KIT exon 11 (9bp insertion/deletion) | |
KIT exon 11 (L575P) and KIT exon 9 (6bp insertion) | |
KIT exon 11 (point mutation) and exon 11 (21 bp in frame deletion) | |
KIT exon 11 (W557R) and KIT exon 11 (G565V) | |
KIT exon 11 (6bp deletion) and KIT exon 13 (V654A) | |
KIT exon 11 (L576P) and KIT exon 13 (V654A) | |
KIT exon 11 (WK557) and KIT exon 13 (V654A) | |
KIT exon 11 (6bp deletion) and KIT exon 17 (Y823D) | |
KIT exon 11 (6bp deletion) and KIT exon 17 (D820Y) | |
KIT exon 13 (V654A) | |
KIT exon 13 (V654A) | |
PDGFR exon 18 D842V | |
PDGFR exon 18 D842V | |
mTOR exon 30 and SDHB exon 2 | |
NF1 (deletion), TERT (amplification), and SDHA (amplification) |
Abbreviations: ECOG, Eastern Cooperative Oncology Group; F, female; M, male.
Missing for 1 patient.