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. Author manuscript; available in PMC: 2018 Jun 15.
Published in final edited form as: Clin Cancer Res. 2016 Dec 22;23(12):2972–2980. doi: 10.1158/1078-0432.CCR-16-2349

Table 1B. Demographics, GIST patients.

n = 20
Gender (M:F) 13:7
Age (median, range) 54 (40–75)
ECOG (median, range) 0 (0–1)
Prior treatments (median, range) 3 (1–8)
Primary site
 Gastric 8
 Small bowel 12
Mutationsa
KIT exon 9 (502_503 duplication)
KIT exon 9 (S501)
KIT exon 9 (6bp deletion) and KIT exon 17 (D820Y)
KIT exon 9 (6bp insertion) and KIT exon 14 (N680K)
KIT exon 11 (9bp insertion/deletion)
KIT exon 11 (L575P) and KIT exon 9 (6bp insertion)
KIT exon 11 (point mutation) and exon 11 (21 bp in frame deletion)
KIT exon 11 (W557R) and KIT exon 11 (G565V)
KIT exon 11 (6bp deletion) and KIT exon 13 (V654A)
KIT exon 11 (L576P) and KIT exon 13 (V654A)
KIT exon 11 (WK557) and KIT exon 13 (V654A)
KIT exon 11 (6bp deletion) and KIT exon 17 (Y823D)
KIT exon 11 (6bp deletion) and KIT exon 17 (D820Y)
KIT exon 13 (V654A)
KIT exon 13 (V654A)
PDGFR exon 18 D842V
PDGFR exon 18 D842V
 mTOR exon 30 and SDHB exon 2
 NF1 (deletion), TERT (amplification), and SDHA (amplification)

Abbreviations: ECOG, Eastern Cooperative Oncology Group; F, female; M, male.

a

Missing for 1 patient.