All comparisons are versus participants with a risk score=0. All models adjusted for age, sex, race, smoking status, diabetes, total cholesterol, HDL-cholesterol, systolic blood pressure and blood pressure medications, and statin medications. The global CVD and mortality models were additionally adjusted for serum creatinine, and the heart failure models were additional adjusted for body mass index and creatinine. CVD=cardiovascular disease; ASCVD=atherosclerotic CVD, CHD=coronary heart disease; CHF=congestive heart failure; CV=cardiovascular